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教員紹介

玉井利代子 教授 [Riyoko Tamai]

担当授業科目
口腔感染症学
主な研究

 著書
1) 口腔微生物学第3版ー感染と免疫ー(共著). [学建書院,2010]
2) 口腔微生物学第4版ー感染と免疫ー(共著). [学建書院,2013]
3) 口腔微生物学第5版ー感染と免疫ー(共著). [学建書院,2015]
4) 口腔微生物学第6版ー感染と免疫ー(共著). [学建書院,2018]
5) 口腔微生物学第7版ー感染と免疫ー(共著). [学建書院,2021]                                          6) 口腔微生物学第8版ー感染と免疫ー(共著). [学建書院,2024]

学術論文

  1. Synergistic effect of Toll-like receptor 2 ligands and alendronate on proinflammatory cytokine production in mouse macrophage-like RAW-ASC cells is accompanied by upregulation of MyD88 expression. Akaho R, Kiyoura Y, Tamai R. J Oral Biosci. 2024 Jun;66(2):412-419. doi: 10.1016/j.job.2024.04.003. Epub 2024 Apr 14.
  2. Alendronate augments lipid A‑induced IL‑1β release by ASC‑deficient RAW264 cells via AP‑1 activation. Watanabe N, Tamai R, Kiyoura Y. Exp Ther Med. 2023 Oct 26;26(6):577. doi: 10.3892/etm.2023.12276. eCollection 2023 Dec.
  3. Alendronate Augments Lipid A-Induced IL-1α Release via Activation of ASC but Not Caspase-11. Tamai R, Mashima I, Kiyoura Y. Inflammation. 2021 Oct;44(5):2132-2141.
  4. Complete Genome Sequence of Veillonella nakazawae JCM 33966T (=CCUG 74597T), Isolated from the Oral Cavity of Japanese Children. Mashima I, Nakazawa F, Tamai R, Kiyoura Y. Microbiol Resour Announc, 2021 Apr 29;10(17):e00279-21.
  5. Veillonella nakazawae sp. nov., an anaerobic Gram-negative coccus isolated from the oral cavity of Japanese children. Mashima I, Theodorea CF, Djais AA, Kunihiro T, Kawamura Y, Otomo M, Saitoh M, Tamai R, Kiyoura Y. Int J Syst Evol Microbiol, 2021 Jan;71(1).
  6. Etidronate down-regulates Toll-like receptor 2 ligand-induced chemokine production by inhibiting MyD88 expression and NF-κB activation. Yambe N, Tamai R, Mashima I, Kiyoura Y. Immunopharmacol Immunotoxicol,  2021 Feb;43(1):51-57.
  7. MPMBP down-regulates Toll-like receptor (TLR) 2 ligand-induced proinflammatory cytokine production by inhibiting NF-κB but not AP-1 activation. Tamai R, Suzuki K, Mashima I, Kiyoura Y. Int Immunopharmacol, 79:106085, 2020.
  8. Heat-killed Candida albicans augments synthetic bacterial component-induced proinflammatory cytokine production. Tamai R, Kiyoura Y. Folia Microbiol, 164:555-66, 2019.
  9. Alendronate augments lipid A-induced IL-1β release and Smad3/NLRP3/ASC-dependent cell death. Tamai R, Kiyoura Y. Life Sci, 198:8-17, 2018.
  10. Extracellular galectin-1 enhances adhesion to and invasion of oral epithelial cells by Porphyromonas gingivalis. Tamai R, Kobayashi-Sakamoto M, Kiyoura Y. Can J Microbiol, 64:465-71, 2018.
  11. Gastrointestinal colonisation and systemic spread of Candida albicans in mice treated with antibiotics and prednisolone. Kobayashi-Sakamoto M, Tamai R, Isogai E, Kiyoura Y. Microb Pathog, 117:191-9, 2018.
  12. Etidronate down-regulates Toll-like receptor (TLR) 2 ligand-induced proinflammatory cytokine production by inhibiting NF-κB activation. Hojo K, Tamai R, Kobayashi-Sakamoto M, Kiyoura Y. Pharmacol Rep, 69:773-8, 2017.
  13. Innate immunity to Candida albicans. Kiyoura Y, Tamai R. Jpn Dent Sci Rev, 51:59-64, 2015.
  14. Candida albicans and Candida parapsilosis rapidly up-regulate galectin-3 secretion by human gingival epithelial cells. Tamai R, Kiyoura Y. Mycopathologia, 177:75-9, 2014.
  15. Amphotericin B up-regulates lipid A-induced IL-6 production via caspase-8. Tamai R, Sugamata M, Kiyoura Y. J Dent Res, 91:709-14, 2012.
  16. Candida albicans enhances invasion of human gingival epithelial cells and gingival fibroblasts by Porphyromonas gingivalis. Tamai R, Sugamata M, Kiyoura Y. Microb Pathog, 51:250-54, 2011.
  17. Alendronate regulates cytokine production induced by lipid A through nuclear factor-κB and Smad3 activation in human gingival fibroblasts. Tamai R, Sugiyama A, Kiyoura Y. J Periodontal Res, 46:13-20, 2011.
  18. Effects of nitrogen-containing bisphosphonates on the response of human peripheral blood mononuclear cells and gingival fibroblasts to bacterial components. Tamai R, Sugiyama A, Kiyoura Y. J Oral Biosci, 52:268-74, 2010.

所属学会・団体名

日本細菌学会

日本免疫学会

歯科基礎医学会

日本エンドトキシン・自然免疫研究会

International Association for Dental Research

Japanese Association for Dental Research

日本老年歯科医学会

日本歯科医学教育学会

日本医学教育学会




インフォメーション

奥羽大学

〒963-8611
福島県郡山市富田町字三角堂31-1
TEL.024-932-8931