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教員紹介

前田 豊信 教授 [Toyonobu Maeda]

担当授業科目
口腔生理・生化学
主な研究

骨芽細胞分化の制御機構の解析
オステオネクチンの生理活性の解析
癌細胞の浸潤転移機構の解析


研究
Kobayashi-Sakamoto M, Maeda T, Kimura M, Yusa J, Ito H, Tani H, Kato Y, Hirose K. Bovine lactoferrin increases the poly(I:C)-induced antiviral response in vitro. Biochem Cell Biol.1;100(4):338-348. 2022

加藤靖正,前田豊信,鈴木厚子.酸性細胞外pH:がん転移に関連する微小環境. 細胞 50(5), 32-36, 2018.

Kojima T, Maeda T, Suzuki A, Yamamori T, Kato Y. Intracellular zinc-dependent TAS2R8 gene expression through CTCF activation. Biomed Res (Tokyo) 41 (5), 217–225, 2020.

Kobayashi-Sakamoto M, Maeda T, Yusa J, Kato Y, Kiyoura Y. RANK-RANKL signaling upregulates Il-10 mRNA expression in mucosal Candida infection in vivo. Microb Pathog 149, 104285, 2020. doi: 10.1016/j.micpath.2020.104285

Sutoo S, Maeda T, Suzuki A, Kato Y. Adaptation to chronic acidic extracellular pH elicits a sustained increase in lung cancer cell invasion and metastasis. Clin Exp Metastasis 37(1), 133-144, 2020. doi: 10.1007/s10585-019-09990-1

Nagaoka M, Maeda T, Chatani M, Handa K, Yamakawa T, Kiyohara S, Negishi-Koga T, Kato Y, Takami M, Niida S, Lang SC, Kruger MC, Suzuki K. A Delphinidin-Enriched Maqui Berry Extract Improves Bone Metabolism and Protects against Bone Loss in Osteopenic Mouse Models. Antioxidants (Basel) 8(9), E386, 2019. doi: 10.3390/antiox8090386

Nagaoka M, Maeda T, Moriwaki S, Nomura A, Kato Y, Niida S, Kruger MC, Suzuki K.. Petunidin, a B-ring 5'-O-methylated derivative of delphinidin, stimulates osteoblastogenesis and reduces sRANKL-induced bone loss. Int J Mol Sci 20(11), 2795, 2019. doi: 10.3390/ijms20112795

Sumida R, Maeda T, Kawahara I, Yusa J, Kato Y. Platelet?rich fibrin increases the osteoprotegerin/receptor activator of nuclear factor?κB ligand ratio in osteoblasts. Exp Ther Med, 2019. doi: https://doi.org/10.3892/etm.2019.7560

Kato Y, Maeda T, Suzuki A, Baba Y. Cancer metabolism: New insights into classic characteristics. Jpn Dent Sci Rev 54(1), 8-21, 2018. doi: 10.1016/j.jdsr.2017.08.003

Maeda T, Suzuki A, Koga K, Miyamoto C, Maehata Y, Ozawa S, Hata RI, Nagashima Y, Nabeshima K, Miyazaki K, Kato Y. TRPM5 mediates acidic extracellular pH signaling and TRPM5 inhibition reduces spontaneous metastasis in mouse B16-BL6 melanoma cells. Oncotarget 8(45), 78312-78326, 2017. doi: 10.18632/oncotarget.20826

Baba Y, Maeda T, Suzuki A, Takada S, Fujii M, Kato Y. Deguelin Potentiates Apoptotic activity of an EGFR tyrosine kinase inhibitor (AG1478) in PIK3CA-mutated head and neck squamous cell carcinoma. Int J Mol Sci 18(2), E262, 2017. doi: 10.3390/ijms18020262

Maeda T, Yuzawa S, Suzuki A, Baba Y, Nishimura Y, Kato Y. RhoA mediates the expression of acidic extracellular pH-induced matrix metalloproteinase-9 mRNA through phospholipase D1 in mouse metastatic B16-BL6 melanoma cells. Int J Oncol 48(3), 1251-1257, 2016. doi: 10.3892/ijo.2016.3322

Maeda T, Suzuki A, Yuzawa S, Baba Y, Kimura Y, Kato Y. Mineral trioxide aggregate induces osteoblastogenesis via Atf6. Bone Rep 2, 36-43, 2015. doi:10.1016/j.bonr.2015.03.003

Suzuki A, Maeda T, Baba Y, Shimamura K, Kato Y. Acidic extracellular pH promotes epithelial mesenchymal transition in Lewis lung carcinoma model. Cancer Cell Int, 2014, 14: 129. doi:10.1186/s12935-014-0129-1

Tsuji K, Maeda T, Kawane T, Matsunuma A, Horiuchi N. Leptin stimulates fibroblast growth factor 23 expression in bone and suppresses renal 1alpha,25-dihydroxyvitamin D3 synthesis in leptin-deficient mice. J. Bone Miner. Res. 25(8): 1711-23, 2010.


所属学会・団体名

歯科基礎医学会
日本生化学会
日本癌学会
日本骨代謝学会
日本がん転移学会
日本結合組織学会
奥羽大学歯学会
みちのく歯学会




インフォメーション

奥羽大学

〒963-8611
福島県郡山市富田町字三角堂31-1
TEL.024-932-8931